If you’re using an acronym that includes trans people, it’s important to actually include trans people in the context of what you are writing about. For example, if you’re only writing about people in same-sex relationships, or if you’re trying to refer to everyone with a marginalized sexuality, don’t use LGBTQ. Some trans people (15%) identify as straight.* LGBTQ and straight/heterosexual are not, therefore, opposites, and should never be treated as such.
Source: The Radical Copyeditor’s Style Guide for Writing About Transgender People | Radical Copyeditor